Wicket-keeper Brad Haddin has been left out of the Australia squad for the first Test against South Africa, which starts in Brisbane on November 9.
The 35-year-old Haddin has an average of 35.82 in his 43 Tests and has just led the Sydney Sixers to victory in the Champions League Twenty20 but he has been replaced by Matt Wade.
Haddin had to leave the tour of the West Indies earlier this year when his daughter fell seriously ill and the 24-year-old Wade impressed as a stand-in, making a century in the third Test.
Aussie skipper Michael Clarke says Haddin will remain in contention and added: "It was a tough decision, there was a lot of talk about that.
"They're two very good wicketkeepers and, whichever way we went, the team was going to be fine.
"Our decision was Matthew Wade and I know he'll do a great job. He's been a wonderful player for Australia in his brief career and he scored a hundred in his last Test match."
Young seamer Pat Cummins was the other notable omission and chief selector John Inverarity said: "We didn't feel as though he was ready to play in a Test.
"We're very keen for him to play a Sheffield Shield match soon, and he's likely to come onto the radar for perhaps the third Test in Perth."
In his absence, his fellow pacemen Peter Siddle, Ben Hilfenhaus, James Pattinson and Mitchell Starc will compete for three spots, unless the Aussies opt for an all-seam attack and leave out spinner Nathan Lyon.
Australia squad: M Clarke (captain), D Warner, E Cowan, S Watson, R Ponting, M Hussey, M Wade, P Siddle, B Hilfenhaus, M Starc, J Pattinson, N Lyon.