Xavier Marshall has been dropped from the West Indies squad for the second Test against England on Friday.
The 22-year-old batsman managed only a two-ball duck in Jamaica as the hosts coasted to an innings and 23 run victory.
Prolific domestic performers Ryan Hinds and Lendl Simmons have therefore been drafted in ahead of the match in Antigua.
Simmons - the nephew of former West Indies batsman Phil Simmons - has yet to make his Test debut, but his double century for West Indies A against England seems to have given him the edge.
Left-hander Hinds at least has some experience in the Test match arena, though, and his 585 runs in seven innings for Barbados at an average of 83.55 make him an attractive prospect.
The 27-year-old's useful left-arm spin has also put him among the Caribbean competition's leading wicket-takers.
Opener Dale Richards and off-spinner Amit Jaggernauth have both been omitted, meanwhile, after being part of the squad at Sabina Park.
West Indies squad: Chris Gayle (captain), Denesh Ramdin, Devon Smith, Lendl Simmons, Ramnaresh Sarwan, Ryan Hinds, Shivnarine Chanderpaul, Brendan Nash, Jerome Taylor, Sulieman Benn, Daren Powell, Fidel Edwards, Lionel Baker.