Tyson Fury's ring return will be against American Joey Abell after original opponent Gonzalo Omar Basile pulled out with a lung infection.
Fury has waited almost 10 months for a heavyweight fight after David Haye pulled out of two scheduled bouts and he will face Abell at the Copper Box Arena in London on February 15.
The Minnesota man has 28 knockouts in his 29 wins, but has lost three of his last five fights.
Kubrat Pulev, a rival contender for Fury, halted Abell in five rounds, but he is refusing to take his replacement foe lightly.
"Abell is big and he can punch - just what I want on my comeback," Fury told espn.co.uk. "One thing I do respect about him is his power. He's got a great knockout record and in the heavyweights it only takes one shot to turn things around."
Fury is on a collision course with Chisora, who is expected to face him in a summer rematch, and the Londoner has also been handed a change of opponent.
Kevin Johnson stepped in at late notice to battle Chisora and Fury is full of respect for the American, having claimed a cagey points win over him in 2012.
Fury found it hard to breach Johnson's defences, but believes the better prepared Chisora will emerge victorious.
"I expect it to be a very good fight but a fit Dereck Chisora should beat a Kevin Johnson who's only had a few weeks notice," said Fury.
"But if Kevin had ten weeks notice, 'Del Boy' would be in trouble cos 'Kingpin's' a helluva fighter; a master boxer with a pack of tricks. But, like when he fought me, Kevin's not really had the time to get himself right."
Exciting prospect Anthony Joshua continued the perfect start to his professional career with a fourth straight knockout win over Dorian Darch on Saturday.
Promoter Eddie Hearn has talked about moving Joshua swiftly towards the likes of Chisora and Fury and the Wilmslow man has mocked these ambitions.
Fury said: "I really hope that Eddie Hearn doesn't start getting ahead of himself and start trying to match him for titles or putting him anywhere near Dereck Chisora as he's foolishly talking about cos he'll get sparked out.
"He's another I want to see get fed easy fights, built up to 20-0. If he gets beat any time soon, there's no mega payday for me down the line. He'd be easy lolly."